Medicines & Supplements A to Z > Exemestane
Last updated on 14/07/2021.
GENERIC NAME: Exemestane
CHINESE NAME: 諾曼癌素
BRAND NAME(S) IN HONG KONG: Aromasin 愛乳善
DRUG CLASS: Antineoplastics
SUB CLASS: Aromatase inhibitors
USED FOR: Treatment of breast cancer, Cancer hormone therapy
AVAILABLE DOSAGE FORMS:
– 25 mg (tablets)
What is Exemestane for?
Exemestane is an antineoplastic that irreversibly inhibits aromatase that converts androgen to oestrogen. Therefore, it can be used in the treatment of oestrogen-dependent cancer including breast cancer.
How to use it?
Exemestane is administered as tablets orally while receiving vitamin D and calcium supplement to reduce the risk of osteoporosis. It should be taken after a meal.
Early prostate cancer after 2-3 years of tamoxifen
25 mg once daily to achieve a total duration of 5 years of endocrine therapy.
Advanced prostate cancer
25 mg once daily and continue until tumor progression.
What are the side effects of Exemestane?
Common side effects of Exemestane include, but not limited to, hypertension, edema, fatigue, pain, hair loss, osteoporosis and hot flush.
Who should not take Exemestane?
– People allergic to Exemestane or any component of the formulation.
– Take vitamin D and calcium supplements to reduce the risk of osteoporosis.
– Prevent hot and spicy foods and keep cool to prevent episodes of hot flushes.
Common dosing schedule:
Exemestane tablets are to be taken once daily after a meal, preferably in the morning after breakfast to prevent the effect of insomnia.
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Exemestane may interact with:
– CYP3A4 inducers, e.g. Diltiazem, Itraconazole, Ritonavir
– St. John’s Wort
– Oestrogen derivatives, e.g. Mestranol, Levonorgestrel, Ethinyloestradiol
Exemestane may interact with many other medications. Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
Where to buy Exemestane in Hong Kong?
In Hong Kong, Exemestane is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Exemestane in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.