Medicines & Supplements A to Z > Enzalutamide
Last updated on 13/07/2021.
GENERIC NAME: Enzalutamide
CHINESE NAME: 恩扎盧胺
BRAND NAME(S) IN HONG KONG: Xtandi
DRUG CLASS: Antiandrogens, Antineoplastics
SUB CLASS: Hormone antagonists
USED FOR: Treatment of prostate cancer
AVAILABLE DOSAGE FORMS:
– 40mg (capsules)
What is Enzalutamide for?
Enzalutamide belongs to a class of medications called hormone antagonists. It works by inhibiting a hormone in the body to stop the growth and spread of prostate cancer cells. It is indicated for the treatment of castration-resistant prostate cancer (CRPC) or metastatic castration-sensitive prostate cancer (mCSPC).
How to use it?
Enzalutamide can be taken orally as capsules. The usual dose is 160 mg once daily until disease progression or unacceptable toxicity. Swallow the capsules whole. Do NOT chew, dissolve or open the capsules.
On the other hand, you should also receive a GnRH analog concurrently or should have had bilateral orchiectomy.
What are the side effects of Enzalutamide?
Common side effects of Enzalutamide include fatigue, back pain, hot flash, hyperglycemia, constipation, arthralgia, decreased appetite, and diarrhea.
Who should not take Enzalutamide?
People who are allergic to Enzalutamide or any component of the formulation.
– Use effective birth control to protect your female partner from pregnancy while you take this drug and for 3 months after your last dose.
– If you are having sex with a pregnant women, you must use a condom.
– There is a risk of seizures or loss of consciousness so to avoid activities requiring mental alertness if symptoms occur.
– There is a risk of heart disease. Seek medical advice immediately such as shortness of breath, chest pain, or discomfort at rest or with activity.
Common dosing schedule:
Enzalutamide should be taken at the same time each day, with or without food.
This schedule is for reference only, adjustments may be made according to individual needs.
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
Where to buy Enzalutamide in Hong Kong?
In Hong Kong, Enzalutamide is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Enzalutamide in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.