Entresto is a brand product that contains Sacubitril and Valsartan, which is a neprilysin inhibitor and angiotensin receptor blocker respectively. Sacubitril helps relax blood vessels and decrease sodium and fluid in the body, while Valsartan reduces blood vessel tightening and the build-up of sodium and fluid. They work in synergy to help improve your heart’s ability to pump blood to the body, hence indicated for the treatment of heart failure.
Entresto is available as tablets. The recommended starting dose is 100 mg twice daily. Within 2-4 weeks to reach a target maintenance dose of 200 mg twice daily.
Paediatric patients or patients with renal/hepatic impairment may require a lower dose.
Common side effects of Entresto include dizziness, light-headedness, and coughing. In rare cases, an allergic reaction might happen, which includes symptoms like difficulty breathing, hives, swelling of face, lips.
Common dosing schedule:
Entresto should be taken twice daily, with or without food. You can take it in the morning and evening.
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Entresto may interact with:
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
In Hong Kong, Entresto is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Entresto in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.
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