Enoxaparin belongs to a class of medications called low molecular weight heparin. It can inhibit several substances involved in the blood clotting process to reduce blood clot formation in your body. It is indicated for unstable angina, myocardial infarction, prevention and treatment of venous thromboembolism (e.g. deep vein thrombosis (DVT)).
Enoxaparin is usually administered by subcutaneous injection for most conditions, but sometimes can be administered by intravenous injection. Listed below are the indications and usual adult dosages, which renal imparied patients, children and elderly may need a lower dose.
For unstable angina, non-ST segment elevation myocardial infarction (non-STEMI):
1 mg/kg subcutaneously every 12 hours for 2-8 days, with oral Aspirin 100-325 mg
For acute ST segment elevation myocardial infarction (STEMI):
30 mg single intravenous bolus plus a 1 mg/kg subcutaneous dose followed by 1 mg/kg subcutaneously every 12 hours for at least 8 days, with oral Aspirin 75-325 mg.
For prophylaxis of DVT in knee or hip replacement surgeries:
30 mg subcutaneously every 12 hours up to 14 days OR 40 mg subcutaneously once daily up to 14 days. The usual duration of administration is 7-10 days.
For prophylaxis of DVT in abdominal surgery:
40 mg subcutaneously once daily up to 12 days. The usual duration of administration is 7-10 days.
For prophylaxis of DVT in medical patients during acute illness:
40 mg subcutaneously once daily up to 14 days. The usual duration of administration is 6-11 days.
For outpatient treatment of acute DVT without pulmonary embolism:
1 mg/kg subcutaneously every 12 hours up to 17 days. Initiate warfarin sodium when appropriate (usually within 72 hours of Enoxaparin), then continue Enoxaparin for at least 5 days and until a therapeutic anticoagulant effect is achieved (INR 2-3).
For inpatient treatment of acute DVT with or without pulmonary embolism:
1 mg/kg subcutaneously every 12 hours up to 17 days. Initiate warfarin sodium when appropriate (usually within 72 hours of Enoxaparin), then continue Enoxaparin for at least 5 days and until a therapeutic anticoagulant effect is achieved (INR 2-3).
Common dosing schedule:
N/A
Some common medications Enoxaparin may interact with:
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
In Hong Kong, Enoxaparin is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Enoxaparin in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.
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