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Doxepin

Last updated on 08/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Doxepin

CHINESE NAME: 杜西平

BRAND NAME(S) IN HONG KONG: Sinequan 神寧健

DRUG CLASS: Antidepressants

SUB CLASS: Tricyclic antidepressants

USED FOR: Depression, Anxiety

AVAILABLE DOSAGE FORMS:
– 10mg, 25mg (capsules)

What is Doxepin for?

Doxepin belongs to a class of medication called tricyclic antidepressants. It is indicated for the treatment of depression and anxiety. It is also recommended as the treatment of depression and/or anxiety associated with alcoholism.

How to use it?

Doxepin is administered orally as tablets. The initial dose for very mild depression/anxiety is 25-50 mg/day, while the initial dose for mild to moderate depression/anxiety is 75 mg/day. You may gradually increase the dose in 25-50 mg increments based on response and tolerability. The usual dosage is 75-150mg in divided doses.

What are the side effects of Doxepin?

Common side effects of Doxepin include dry mouth, dizziness, blurred vision, constipation, drowsiness, or nausea.

Who should not take Doxepin?

– People who are allergic to Doxepin or any component of the formulation
– Patients with glaucoma, urinary problems
– Patients taking monoamine oxidase inhibitors, such as Selegiline, Rasagiline

Pharmacist Tips:

– It might take a few weeks for Doxepin to have symptomatic improvement in depression. Do not stop taking Imipramine suddenly during that time.
– Avoid driving or operating machinery until you know how you respond to Doxepin.
– Patients should not drink alcohol during the treatment.

Common dosing schedule:
Doxepin can be taken with or without food. You may take your total daily dosage in divided, or once a day dosage at bedtime (if dose < 100 mg).

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Doxepin may interact with:
Cimetidine
– Tolazamide
– Quinidine
– Antidepressants, e.g. Fluoxetine, Paroxetine

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Doxepin in Hong Kong?

In Hong Kong, Doxepin is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Doxepin in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.