Medicines & Supplements A to Z > Domperidone


Last updated on 09/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Domperidone 



DRUG CLASS: Gastrointestinal drugs, Antiemetics

SUB CLASS: Dopamine antagonists

USED FOR: Nausea and vomiting, Abnormal GI motility

– 10mg (tablets)
– 1mg/ml, 5mg/ml, 10mg/ml (syrups)

What is Domperidone for?

Domperidone belongs to a class of medications called dopamine antagonists. It can increase gastric motility and peristalsis to treat gastrointestinal (GI) motility disorders. On the other hand, it can suppress a chemical in the brain which causes  nausea and vomiting.

How to use it?

Domperidone can be taken orally as conventional tablets or syrups. For both indications, the usual dose is 10 mg three times a day.

What are the side effects of Domperidone?

Common side effects of Domperidone include headache, dry mouth, or migraine.

Who should not take Domperidone?

– People who are allergic to Domperidone or any component of the formulation
– Patients with moderate or severe hepatic impairment, prolactinoma, GI hemorrhage, mechanical obstruction, or perforation
– Patients with conditions where cardiac conduction is known to be impaired, underlying cardiac disease, electrolyte disturbances

Pharmacist Tips:

This drug may cause side effects to your heart. Report any signs of abnormal heartbeat or chest pain immediately.

Common dosing schedule:
Domperidone should be administered 15-30 minutes prior to meals.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Domperidone may interact with:
– Antibiotics, e.g. Clarithromycin, Erythromycin
– Antiarrhythmics, e.g. Amiodarone, Sotalol
– Antifungals, e.g. Ketoconazole, Itraconazole

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Domperidone in Hong Kong?

In Hong Kong, Domperidone is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Domperidone in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.