Medicines & Supplements A to Z > Dobutamine

Dobutamine

Last updated on 04/08/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Dobutamine

CHINESE NAME: 多保他命

BRAND NAME(S) IN HONG KONG: Dobutel, Dobutamine-Halemn

DRUG CLASS: Inotropic agents

SUB CLASS: Catecholamine

USED FOR: Cardiogenic shock

AVAILABLE DOSAGE FORMS:
– 250 mg/20ml, 250 mg/5ml (injections)

What is Dobutamine for?

Dobutamine belongs to a class of medications called inotropic agents acting on alpha-1, beta-1, predominantly, and beta-2 receptors. It can improve the force of contraction of the heart and the heart rate and dilate the blood vessels. Dobutamine is used for treating cardiogenic shock.

How to use it?

Dobutamine is injected through a needle into a vein as directed by your doctor. Your doctor will advise you on the dosage and frequency depending on your cardiogenic shock.

Cardiogenic shock
Adult and elderly
0.5-40 mcg/kg/min. The dose is adjusted according to your conditions, including your blood pressure, heart rate, heart output and urine output.

Child
The initial dose is 5 mcg/kg/min. The dose is adjusted to 2-20 mcg/kg/min according to your conditions, including your blood pressure, heart rate, heart output and urine output.

What are the side effects of Dobutamine?

Common side effects of Dobutamine include, but not limited to, faster heartbeats, increased blood pressure, chest pain, headache, nausea and shortness of breath.

Who should not take Dobutamine?

– People allergic to Dobutamine, sulphites or any component of the formulation.
– Patients with hypertrophic cardiomyopathy with outflow tract obstruction/idiopathic hypertrophic subaortic stenosis.

Pharmacist Tips:

– Coronary artery bypass surgery may be needed if your condition is severe.

Common dosing schedule:
The intravenous injection is infused as directed by your physicians until the parameter reaches its target, for instance, when your blood pressure returns to normal.

This schedule is for reference only, adjustments may be made according to individual needs. 

Some common medications Dobutamine may interact with:
– Beta blockers, e.g. Bisoprolol, Metoprolol, Propranolol
– COMT inhibitors, e.g. Entacapone, Tolcapone, Opicapone
– Sympathomimetics, e.g. Amphetamines, Pseudoephedrine
Atomoxetine
Linezolid

Dobutamine may interact with many other medications. Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Dobutamine in Hong Kong?

In Hong Kong, Dobutamine is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Dobutamine in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.