Medicines & Supplements A to Z > Dexlansoprazole

Dexlansoprazole

Last updated on 25/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Dexlansoprazole

CHINESE NAME: 右蘭索拉唑

BRAND NAME(S) IN HONG KONG: Dexilant 特胃能

DRUG CLASS: Gastrointestinal Drugs

SUB CLASS: Proton Pump Inhibitors

USED FOR: Gastroesophageal Reflux Disease (GERD)

AVAILABLE DOSAGE FORMS:
– 30 mg, 60 mg (delayed-release capsules)

What is Dexlansoprazole for?

Gastroesophageal Reflux Disease (GERD) is a disease whose gastric content flows back to the esophagus. GERD may be triggered after meals, especially after eating spicy food, oily food or alcoholic drinks. Dexlansoprazole, a proton pump inhibitor,  strongly inhibits the secretion of gastric acid in the stomach by blocking the “proton pumps” in stomach cells.

How to use it?

Dexlansoprazole is available in delayed-release capsules for oral use for longer duration of action. It can be taken with or without food. Do not crush, chew or open the capsules unless instructed. 

Non-erosive Gastroesophageal Reflux Disease (GERD)
Child, adult and elderly
30 mg once daily for 4 weeks, continue if not recovered fully. 

Erosive Gastroesophageal Reflux Disease (GERD)
Child, adult and elderly
60 mg once daily for 8 weeks, then switch to 30 mg once daily for maintenance. Stop when asymptomatic.

What are the side effects of Dexlansoprazole?

Common side effects of Dexlansoprazole include nausea, diarrhoea, dizziness and headache.

Who should not take Dexlansoprazole?

– Patients with fractures.
– Patients with severe liver impairment.
– Patients with hypomagnesemia.
– Pregnant and breastfeeding women
– People allergic to Dexlansoprazole and any components in the formulation

Pharmacist Tips:

– There is a risk of osteoporosis for Dexlansoprazole users in advanced age and postmenupausal women. Make sure to take enough calcium and vitamin D.
– Dexlansoprazole may mask the alarming symptoms of gastric cancer. It should be eliminated before treatment.
– Patients with moderate liver impairment may need dose reductions. 

Common dosing schedule:
Dexlansoprazole is to be taken once daily.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Dexlansoprazole may interact with:
Phenytoin
– Bisphosphonate derivatives, e.g. Alendronate, Zoledronic acid
Dipyridamole
– Glucocorticoids, e.g. Budesonide, Dexamethasone

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Dexlansoprazole in Hong Kong?

In Hong Kong, Dexlansoprazole is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Dexlansoprazole in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.