Danazol belongs to the class of endocrine drugs. It is an androgen resembling male sex hormones to inhibit female sex hormones so as to treat endometriosis and hereditary angioedema.
Danazol is taken orally as capsules. Taking on either an empty stomach or after meals is acceptable, but the timing has to be consistent throughout the regimen.
200-400 mg daily in 2 divided doses initially. Reduce dose gradually to maintain the absence of menstruation. Danazol should be used continuously for 3-9 months.
Moderate to severe endometriosis
800 mg daily in 2 divided doses initially. Reduce dose gradually to maintain the absence of menstruation. Danazol should be used continuously for 3-9 months.
Long-term prevention of hereditary angioedema
100-200 mg once daily. Reduce dose gradually depending on the frequency of attack.
Child ≥16 years of age
Initially 2.5 mg/kg daily at a maximum dose of 50 mg daily. Increase the dose slowly biweekly to a maximum dose of 5 mg/kg daily or 200 mg daily depending on which one is smaller. Reduce dose gradually depending on the control of the angioedema.
Common dosing schedule:
Depending on the indication, Danazol can be taken once to twice daily.
For those taking it once daily, Danazol can be taken around breakfast.
For those taking it twice daily, Danazol can be taken around breakfast and dinner.
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Danazol may interact with:
Danazol may interact with many other medications. Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
In Hong Kong, Danazol is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Danazol in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.
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