Medicines & Supplements A to Z > Colchicine
Last updated on 19/03/2021.
GENERIC NAME: Colchicine
CHINESE NAME: 秋水仙鹼
BRAND NAME(S) IN HONG KONG: Colgout, Colcina, Kolcine
DRUG CLASS: Anti-gout agents
USED FOR: Prevent gout attack and familial Mediterranean fever
OTHER DRUGS IN THE SAME CLASS: Allopurinol, probenecid
What is Colchicine for?
Colchicine is a medicine for treating and preventing gout attack as well as familial Mediterranean fever. It works by preventing the accumulation of uric acid crystals and hence relieving pain and also stopping the process that results in swelling.
Colchicine does not cure gout, but is used to treat and prevent gout attacks.
How to use it?
Colchicine can be taken by mouth as tablets. For the acute treatment of gout flares, the usual dose on day 1 is 1 mg (or 1.2 mg) once, followed in one hour by 0.5 mg (or 0.6 mg) once. An alternative dosing regimen is 0.5 mg (or 0.6 mg) 3 times daily. On day 2, you then would take 0.5 mg (or 0.6 mg) once or twice daily. Many people continue this dose until the flare is resolved or for 2-3 days after the flare resolves. For the prevention of gout when starting antigout agents like Allopurinol, doses range from 0.5 mg (or 0.6 mg) once or twice daily. For the prevention of attacks in familial Mediterranean fever, dosages are usually 0.5-3 mg once daily.
What are the side effects of Colchicine?
Side effects of Colchicine include abdominal pain, diarrhoea, nausea and vomiting. Colchicine has many food and drug interactions so always check with your pharmacist or doctor before taking new medications. Grapefruit juice or pomelo should be avoided while taking Colchicine.
Who should not take Colchicine?
– Anyone who has both renal and hepatic impairment
– Anyone who is using Colchicine together with P-glycoprotein or CYP3A4 inhibitors (e.g. clarithromycin, ritonavir)
Do not discontinue the drug without your doctor’s consultation. A proper withdrawal plan should be discussed with your doctor to avoid withdrawal symptoms.
Common dosing schedule:
Can be taken with or without food
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Colchicine may interact:
– CYP3A4 inhibitors e.g. Clarithromycin, ritonavir
– Antihepaciviral combination products e.g. ombitasvir, ritonavir
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
Where to buy Colchicine in Hong Kong?
In Hong Kong, Colchicine is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk/
Need more information?
For detailed information about the use of Colchicine in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.