Co-Codamol

Fact Checked

Medically reviewed by Kenny Cheuk Yin Cheung, Pharmacist

Last updated on 02/07/2021.

GENERIC NAME: Codeine phosphate + Paracetamol

CHINESE NAME: 磷酸可待因 + 撲熱息痛

DRUG CLASS: Analgesics

SUB CLASS: Nonsteroidal Anti-Inflammatory Drugs, Opioid Analgesics

USED FOR: Pain relief, fever

AVAILABLE DOSAGE FORMS:
– 8mg/500mg (tablets)

What is Co-Codamol?

Co-Codamol is a brand of product that contains Paracetamol (non-opioid analgesic) and Codeine (opioid analgesic) as active ingredients. Co-Codamol is used for the relief of mild to moderate pain and to reduce body temperature in fever.

How to use it?

Co-Codamol is available in tablets which are taken by mouth. You can take Co-Codamol with or without food. Taking it with food may help to reduce gastrointestinal discomfort.

For adults and children over 12 years, take 1-2 tablets every 4-6 hours when necessary. The maximum dosage is 8 tablets per day.

For children 6-12 years, take ½-1 tablet every 4-6 hours when necessary. The maximum dosage is 4 tablets per day.

What are the side effects of Co-Codamol?

Common side effects of Co-Codamol include constipation, dizziness and drowsiness, dry mouth, euphoric mood, flushing, hallucinations, nausea and vomiting (more common on initiation), respiration depression (with high dose). Like all opioid medications, people can become tolerant or addicted to Co-Codamol, which can result in withdrawal symptoms when you try to stop the medicine.

Who should not take Co-Codamol?

– People allergic to Co-Codamol or any component of the formulation
– Patients with respiratory depression, serious bronchial asthma or gastrointestinal obstruction
– People who are taking or took monoamine oxidase inhibitors (MAOIs) within the past 14 days

Pharmacist Tips:

– If you are using multiple cough and cold or pain products, make sure that you do not double up on Paracetamol to avoid using more than the maximum recommended daily dose.
– Note that opioids have the potential to be addictive and you can become tolerant over time.
– Tell your doctor if you experience severe side effects, such as difficulty breathing.
– Do not stop the medication abruptly if you have used Co-Codamol over long periods of time.
– Eat more high-fibre foods, drink more water and do more exercise to reduce the side effects of constipation.
– It is best to avoid alcohol while taking Co-Codamol.

Common dosing schedule:
Co-Codamol may be used every 4-6 hours or as required. Take Co-Codamol after food with a drink of water.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Co-Codamol may interact with:
– Antidepressants, e.g. Amitriptyline, Doxepin
– Benzodiazepines, e.g. Lorazepam, Midazolam
– Antihypertensives, e.g. Atenolol, Verapamil
– Monoamine oxidase inhibitors, e.g. Isocarboxazid, Selegiline
– Warfarin
– Isoniazid

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Co-Codamol in Hong Kong?

In Hong Kong, Co-Codamol is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Co-Codamol in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.