Medicines & Supplements A to Z > Cinacalcet


Last updated on 25/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Cinacalcet



DRUG CLASS: Antiresorptive agents

SUB CLASS: Calcimimetics

USED FOR: Lowering calcium levels, Secondary hyperparathyroidism

– 25 mg (tablets)

What is Cinacalcet for?

Cinacalcet belongs to a class of medications called antiresorptive agents acting on calcium-sensing receptors to increase its sensitivity and lower parathyroid hormone. Cinacalcet is used for lowering calcium levels and treating secondary hyperparathyroidism.

How to use it?

Cinacalcet is taken as oral tablets. It is administered with food or shortly after a meal. Do not chew, crush, or divide the tablet and swallow as a whole. 

Secondary hyperthyroidism
Adult and elderly
25 mg once daily and increase every 3 weeks by 25 mg up to 100 mg once daily.

What are the side effects of Cinacalcet?

Common side effects of Cinacalcet include, but not limited to, hypotension, hypocalcemia, nausea, vomiting, diarrhoea, headache, muscle spasm and pain and shortness of breath.

Who should not take Cinacalcet?

– People allergic to Cinacalcet or any component of the formulation.
– People with a serum calcium level lower than the lower limit of the normal range.

Pharmacist Tips:

– For some people, your serum calcium level may be excessively lowered by Cinacalcet. There are signs and symptoms like tingling, muscle spasm, convulsions, tetany and muscle stiffening. If this is the case, report these signs and symptoms to your physician as soon as possible.

Common dosing schedule:
The oral tablet is taken once daily. For example, it can be taken before breakfast. It is administered with food or shortly after a meal. Do not chew, crush, or divide the tablet and swallow as a whole.

This schedule is for reference only, adjustments may be made according to individual needs. 

Some common medications Cinacalcet may interact with:
– CYP2D6 substrates, e.g. Desipramine, Dextromethorphan, Haloperidol
– CYP3A4 inhibitors, e.g. Fosaprepitant, Clofazimine, Brexpiprazole
– Etelcalcetide
– Denosumab

Cinacalcet may interact with many other medications. Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Cinacalcet in Hong Kong?

In Hong Kong, Cinacalcet is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Cinacalcet in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.