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Chlordiazepoxide

Last updated on 24/03/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions   |   Tips   |   Where To Buy  

GENERIC NAME: Chlordiazepoxide 

CHINESE NAME: 氯氮卓 

BRAND NAME(S) IN HONG KONG: Litamin, Medocalum (Contains Chlordiazepoxide and Clidinium Bromide)

DRUG CLASS: Benzodiazepine 

USED FOR: Anxiety, alcohol withdrawal syndrome 

OTHER DRUGS IN THE SAME CLASS: Alprazolam, Bromazepam, Clobazam, Clonazepam, Diazepam, Lorazepam, Midazolam, Temazepam, Nitrazepam, Pinazepam, Triazolam

AVAILABLE DOSAGE FORMS:
– 2.5mg, 5mg (capsules)
– 5mg (tablets)

What is Chlordiazepoxide for?

Chlordiazepoxide belongs to a class of medications called benzodiazepines just like Alprazolam. It can be used for short-term management of anxiety. Chlordiazepoxide is also taken for symptoms associated with alcohol withdrawal syndrome.

How to use it?

Chlordiazepoxide is given by mouth as tablets and capsules. 

If you are taking Chlordiazepoxide for anxiety, you should take 5-10 mg 3 times daily. 

If you are taking Chlordiazepoxide for alcohol withdrawal, the dose ranges from 10-50 mg 4 times each day. Your dose will be cut down gradually over 5-10 days.

What are the side effects of Chlordiazepoxide?

Common side effects of Chlordiazepoxide include decreased alertness, dizziness and drowsiness. Gait and coordination problems (ataxia) and confusion are more commonly seen in elderly; whereas respiratory depression may occur with high doses of Chlordiazepoxide when combined with opioid medications.

Who should not take Chlordiazepoxide?

– People who are allergic to Chlordiazepoxide or any formulation component
– Patients with acute lung insufficiency, chronic psychosis, or sleep apnea
– Patient with severe respiratory insufficiency, especially if using opioids, since there will be an increased risk of death due to respiratory depression caused by Chlordiazepoxide
– Anyone with a history of substance abuse since there is a risk of abuse with benzodiazepines

Pharmacist Tips:

– Avoid using opioids or alcohol with Benzodiazepines.
– Patients should avoid abrupt discontinuation of the drug to prevent withdrawal symptoms. Discuss how to stop Chlordiazepoxide safely with your doctor or pharmacist.
– Avoid activities requiring mental alertness or coordination such as driving until you know how you respond to Chlordiazepoxide.
– Many people who take Chlordiazepoxide on a regular basis will become dependent on the drug.

Common dosing schedule:
You can take Chlordiazepoxide with or without food.
Do not take with grapefruit juice. 

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Chlordiazepoxide may interact with:
– Atypical antipsychotics, e.g. Clozapine, Olanzapine
– CNS depressants, e.g. Buprenorphine
– Flunitrazepam
– Fusidic Acid– Oxycodone

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Chlordiazepoxide in Hong Kong?

In Hong Kong, Chlordiazepoxide is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Chlordiazepoxide in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.