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Chloral Hydrate

Last updated on 15/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions   |   Tips   |   Where To Buy  

GENERIC NAME: Chloral Hydrate

CHINESE NAME: 水合氯醛

BRAND NAME(S) IN HONG KONG: PMS-Chloral Hydrate Syrup

DRUG CLASS: Hypnotics

SUB CLASS: Non-benzodiazepines

USED FOR: Sedation

AVAILABLE DOSAGE FORMS:
– 100 mg/ml, 1 g/5ml (syrups)

What is Chloral Hydrate for?

Chloral Hydrate is a non-benzodiazepine hypnotic with an unknown mechanism of action, used for procedural sedation.

How to use it?

Chloral Hydrate is taken orally as syrups. Taking on either an empty stomach or after meals is acceptable, but the timing has to be consistent throughout the regimen. The syrup may also be diluted in water or other liquid to minimize gastric irritation.

Procedural sedation
Adult
500-1000 mg 30 minutes prior to the procedure.

Infants and children < 3 years of age
25-100 mg/kg 30 minutes prior to procedure up to 1,000 mg and may repeat after 30 minutes with 25 to 50 mg/kg if necessary. In total, it should not exceed 100 mg/kg or 2,000 mg.

Sedation in mechanically-ventilated patients
Infants, children and adolescents
The initial dose is 8 to 25 mg/kg every 6-8 hours, and increases based on body response up to 50 mg/kg or 1000 mg every 6 hours.

What are the side effects of Chloral Hydrate?

Common side effects of Chloral Hydrate include hypotension, arrhythmia, fatigue, skin rash and diarrhea.

Who should not take Chloral Hydrate?

– People who are allergic to Chloral Hydrate or any component of the formulation
– Patients with marked liver or kidney impairment

Pharmacist Tips:

– The syrup may also be diluted in water or other liquid to minimize gastric irritation.

Common dosing schedule:
Chloral Hydrate will be prescribed before medical procedures by healthcare professionals or when you are hospitalized.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Chloral Hydrate may interact with:
– Doxylamine
– Chlormethiazole
– Hydroxyzine
– Magnesium Sulphate
– Warfarin

Chloral Hydrate may interact with many other medications. Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Chloral Hydrate in Hong Kong?

In Hong Kong, Chloral Hydrate is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Chloral Hydrate in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.