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Ceftriaxone

Last updated on 05/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Ceftriaxone

CHINESE NAME: 頭孢曲松

BRAND NAME(S) IN HONG KONG: Rocephin 羅氏芬

DRUG CLASS: Antibiotics

SUB CLASS: Cephalosporins (Third Generation)

USED FOR: Susceptible infections, bacterial meningitis, acute otitis media, sexually transmitted infections, gonorrhoea, urinary tract infections (UTIs), respiratory tract infections, pneumonia, bone and joint infections, skin and soft tissue infections, intra-abdominal infections, prevention of surgical infections

AVAILABLE DOSAGE FORMS:
– 250 mg, 500 mg, 1 g, 2 g (injections/infusions)

What is Ceftriaxone for?

Ceftriaxone belongs to a class of medications called cephalosporin antibiotics. It kills bacteria by interrupting the integrity of bacterial cell walls. It is used to treat infections, including gonorrhea (a sexually transmitted disease), genital infections, bacterial meningitis, as well as respiratory tract infections, bone and joint infections, and skin and soft tissue infections. Ceftriaxone is also used for the prevention of postoperative infections. Ceftriaxone does not work for virus or fungus infections.

How to use it?

Ceftriaxone is injected through a needle into a vein or muscle as directed by your doctor. Your doctor will advise you on the dosage and frequency depending on your infection.

Susceptible infections
Adult
1-2 g once daily. Increase to 4 g daily in severe infections.
Child over 12 years
Body weight >50 kg: 0.5-1 g once daily. Increase to 4 g daily in severe infections.
Child 15 days – 12 years
Body weight <50 kg: 50-80 mg/kg body weight once daily via IV infusion over at least 30 minutes. Increase to 100 mg/kg for severe infections. Maximum dose is 4 g daily.
Child under 15 days
20-50 mg/kg body weight daily via IV infusion over 60 minutes.

Acute otitis media
Adult
1-2 g daily as a single dose.
Child
Body weight >50 kg: 1-2 g daily as a single dose.
Body weight <50 kg: 50 mg/kg body weight as a single dose.

Uncomplicated gonorrhoea
Adult
250-500 mg as a single dose.

Syphilis
Adult
0.5-1 g once daily.
Child over 12 years
Body weight >50 kg: 0.5-1 g once daily.
Child 15 days – 12 years
Body weight <50 kg: 75-100 mg/kg body weight daily via IV infusion over at least 30 minutes for 10-14 days. Maximum dose is 4 g daily.
Child under 15 days
50 mg/kg body weight daily via IV infusion over 60 minutes.

Lyme disease
Adult
2 g once daily for 14-21 days.
Child over 12 years
Body weight >50 kg: 2 g once daily for 14-21 days.
Child 15 days – 12 years
Body weight <50 kg: 50-80 mg per kg body weight once daily for 14-21 days.

Prevention of surgical infections
Adult
1-2 g to be administered 0.5-2 hours before surgery.
Child over 12 years
Body weight >50 kg: 1-2 g to be administered 0.5-2 hours before surgery.
Child 15 days – 12 years
Body weight <50 kg: 50-80 mg/kg body weight as a single dose before surgery via IV infusion over at least 30 minutes.
Child under 15 days
20-50 mg/kg body weight as a single dose before surgery via IV infusion over 60 minutes.

What are the side effects of Ceftriaxone?

Common side effects of Ceftriaxone include anaemia, abdominal pain, diarrhoea, dizziness, headache, nausea and vomiting, and allergic skin reactions.

Who should not take Ceftriaxone?

– People allergic to Ceftriaxone or any component of the formulation.
– People who are allergic to beta-lactams, e.g. Penicillins and Cephalosporins.

Pharmacist Tips:

– Report severe diarrhoea and ask your doctor or pharmacist before taking antidiarrheal medicines.
– Drink plenty of water to replace any lost fluids due to diarrhoea.

Common dosing schedule:
Ceftriaxone is usually administered once daily.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Ceftriaxone may interact with:
Warfarin
– Aminoglycoside antibiotics, e.g. Amikacin, Gentamicin, Tobramycin
– Antidiarrheal medications

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Ceftriaxone in Hong Kong?

In Hong Kong, Ceftriaxone is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.  

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Ceftriaxone in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.