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Cefotaxime

Last updated on 05/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions   |   Tips   |   Where To Buy  

GENERIC NAME: Cefotaxime

CHINESE NAME: 頭孢唑肟

BRAND NAME(S) IN HONG KONG: Claforan 可活能

DRUG CLASS: Antibiotics

SUB CLASS: Cephalosporins (Third Generation)

USED FOR: Bacterial meningitis, sexually transmitted infections, gonorrhoea, urinary tract infections (UTIs), respiratory tract infections, pneumonia, bone and joint infections, skin and soft tissue infections, intra-abdominal infections, prevention of surgical infections

AVAILABLE DOSAGE FORMS:
– 500 mg, 1 g, 2 g (injections/infusions)

What is Cefotaxime for?

Cefotaxime belongs to a class of medications called cephalosporin antibiotics. It kills bacteria by interrupting the integrity of bacterial cell walls. It is used to treat infections, including pneumonia (respiratory tract infection), gonorrhea (a sexually transmitted disease), bacterial meningitis, bone and joint infections, and skin and soft tissue infections. Cefotaxime is also used for the prevention of postoperative infections. Cefotaxime does not work for virus or fungus infections.

How to use it?

Cefotaxime is injected through a needle into a vein or muscle as directed by your doctor. Your doctor will advise you on the dosage and frequency depending on your infection.

Gonorrhoea
Adult
500 mg or 1 g as a single dose.
Child
500 mg as a single dose.

Bacterial infections
Adult
1-2 g every 8-12 hours depending on the severity of the infection. Maximum dose is 12 g daily.
Child 1 month – 12 years
Body weight <50 kg: 50-180 mg/kg body weight in 4-6 divided doses.
Neonate 1-4 weeks
50 mg/kg body weight per dose every 8 hours.
Newborn under 1 week
50 mg/kg body weight per dose every 12 hours.

Prevention of surgical infections
Adult
1 g to be administered 0.5-1.5 hours before surgery.

What are the side effects of Cefotaxime?

Common side effects of Cefotaxime include abdominal pain, diarrhoea, dizziness, headache, nausea and vomiting, and allergic skin reactions.

Who should not take Cefotaxime?

– People allergic to Cefotaxime or any component of the formulation.
– Anyone who is allergic to cephalosporins.

Pharmacist Tips:

– Report severe diarrhoea and ask your doctor or pharmacist before taking antidiarrheal medicines.
– Drink plenty of water to replace any lost fluids due to diarrhoea.
– If you experience symptoms like skin rash or enlarged lymph nodes, report to your doctor immediately.

Common dosing schedule:
Cefotaxime is usually administered every 8-12 hours.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Cefotaxime may interact with:
– Warfarin
– Aminoglycoside antibiotics, e.g. Amikacin, Gentamicin, Tobramycin
– Antidiarrheal medications

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Cefotaxime in Hong Kong?

In Hong Kong, Cefotaxime is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.  

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Cefotaxime in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.