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Cefazolin

Last updated on 05/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Cefazolin

ALTERNATIVE NAME: Cefazoline, Cephazolin

CHINESE NAME: 頭孢唑林

BRAND NAME(S) IN HONG KONG: Stazolin 賜爾寧

DRUG CLASS: Antibiotics

SUB CLASS: Cephalosporins (First Generation)

USED FOR: Bacterial infections, urinary tract infections (UTIs), respiratory tract infections, pneumonia, bone and joint infections, skin and soft tissue infections, intra-abdominal infections, prevention of surgical infections

AVAILABLE DOSAGE FORMS:
– 1 g (injections)

What is Cefazolin for?

Cefazolin belongs to a class of medications called cephalosporin antibiotics. It kills bacteria by interrupting the integrity of bacterial cell walls. It is used to treat infections, including urinary tract infections (UTIs), genital infections, respiratory tract infections (e.g. pneumonia), bone and joint infections, skin and soft tissue infections. Cefazolin is also used for the prevention of postoperative infections. Cefazolin does not work for virus or fungus infections.

How to use it?

Cefazolin is injected through a needle into a vein or muscle as directed by your doctor. Your doctor will advise you on the dosage and frequency depending on your infection.

Treatment of bacterial infections
Adult
1-2 g daily in 2-3 divided doses, maximum dosage of 12 g daily for severe infections.
Child 1 year and above
25-50 mg per kg body weight daily in 2-4 divided doses, maximum dosage of 100 mg/kg in divided doses for severe infections.

Prevention of surgical infections
Adult
1 g to be administered 30-60 minutes before surgery, then 0.5-1 g if required, during surgery (in procedures lasting 2 hours or more)
Child 12-17 years
Body weight >40 kg: 1 g to be administered 30-60 minutes before surgery, then 0.5-1 g if required, during surgery (in procedures lasting 2 hours or more)

What are the side effects of Cefazolin?

Common side effects of Cefazolin include decreased appetite, abdominal pain, diarrhoea, dizziness, headache, nausea and vomiting, and allergic skin reactions.

Who should not take Cefazolin?

– People allergic to Cefazolin or any component of the formulation.
– Anyone who is allergic to cephalosporins.

Pharmacist Tips:

– Report severe diarrhoea and ask your doctor or pharmacist before taking antidiarrheal medicines.
– Drink plenty of water to replace any lost fluids due to diarrhoea.

Common dosing schedule:
Cefazolin is administered 2-4 times daily.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Cefazolin may interact with:
Warfarin
– Antidiarrheal medications
Gentamicin
Probenecid

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Cefazolin in Hong Kong?

In Hong Kong, Cefazolin is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.  

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Cefazolin in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.