Medicines & Supplements A to Z > Bupivacaine
Last updated on 01/07/2021.
GENERIC NAME: Bupivacaine
CHINESE NAME: 布比卡因
BRAND NAME(S) IN HONG KONG: Marcain 麻卡因
DRUG CLASS: Analgesics
SUB CLASS: Local anesthetics
USED FOR: Acute pain management, surgical anaesthesia
AVAILABLE DOSAGE FORMS:
– 0.5% (injections)
What is Bupivacaine for?
Bupivacaine belongs to a class of medications called local analgesics. It works by blocking nerve signals of pain in your body and is therefore used to reduce pain in surgical procedures, dental practices and childbirth.
How to use it?
Bupivacaine is injected through a needle directly into or near the area to be numbed in dental or hospital settings.
For an epidural, bupivacaine is injected in your middle or lower back near your spine. The common dosage for an epidural anesthesia is 50-150 mg, administered using a 2.5 mg/mL or 5 mg/mL solution.
For Cesarean section under spinal anesthesia, the common dosage is 6.25-12.5 mg/hour of 0.125% Bupivacaine solution.
For a dental procedure, bupivacaine is injected into the mouth near the tooth or teeth your dentist will be working on.
The maximum dosage of Bupivacaine is 175 mg per dose, and 400 mg per 24 hours.
What are the side effects of Bupivacaine?
Common side effects of Bupivacaine include numbness and swelling and at injection site, headache, nausea and dizziness.
Who should not take Bupivacaine?
People allergic to Bupivacaine or any component of the formulation.
– Patients who are administered local anesthetics are at increased risk of developing methemoglobinemia. If you experience symptoms like rapid heart rate, shortness of breath and fatigue, report to your doctor immediately.
Common dosing schedule:
Bupivacaine is injected to the required sites by a medical professional prior to surgical procedures. It may be administered once, multiple times or continuously as infusion depending on the conditions.
Some common medications Bupivacaine may interact with:
Lignocaine may increase your risk of developing methemoglobinemia when concurrently using the following drugs:
– Other local anesthetics, e.g. Articaine, Lignocaine, Procaine, Prilocaine
– Nitrates, e.g. Nitroglycerin, Nitric oxide, Isosorbide Mononitrate and Dinitrate
– Antibiotics, e.g. Dapsone, Sulfonamides
– Anticonvulsants, e.g. Phenobarbital, Phenytoin, Sodium Valproate
– Acetaminophen, Metoclopramide, Sulfasalazine
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
Where to buy Bupivacaine in Hong Kong?
In Hong Kong, Bupivacaine is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Bupivacaine in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.