Medicines & Supplements A to Z > Brimonidine

Brimonidine

Last updated on 08/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions   |   Tips   |   Where To Buy  

GENERIC NAME: Brimonidine

CHINESE NAME: 溴莫尼定

BRAND NAME(S) IN HONG KONG: Alphagan P, Mirvaso

DRUG CLASS: Anti-glaucoma agents, Vasoconstrictors

SUB CLASS: Alpha agonists

USED FOR: Glaucoma, Ocular hypertension, Rosacea

AVAILABLE DOSAGE FORMS:
– 0.33% (Mirvaso®) (gel)
– 0.15%, 0.2% (eye drops)

What is Brimonidine for?

Brimonidine belongs to a class of medications called alpha-2 adrenergic receptor agonists. It can decrease formation of aqueous humor in eyes and increase its excretion in order to lower intraocular pressure. Therefore, Brimonidine eye drops are indicated for the 2nd line treatment of glaucoma and ocular hypertension.

On the other hand, Brimonidine gel can narrow blood vessels when applied topically to treat a skin condition called rosacea.

How to use it?

Brimonidine can be administered topically as gel, or applied to eyes.

For glaucoma and ocular hypertension (0.15%, 0.2% eye drops):
Instill 1 drop in affected eye(s) 3 times a day. 

Lie down or tilt your head back. With your index finger, pull down the lower lid of your eye. Hold the dropper close to your eye with the other hand, and drop 1 drop into your eyes between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute.

For rosacea (0.33% gel):
Apply a pea-size amount once daily as a thin layer across the entire face covering the central forehead, each cheek, nose, and chin, avoiding the eyes and lips. Wash hands immediately after applying.

What are the side effects of Brimonidine?

The common side effects of Ophthalmic Brimonidine include ocular hyperemia, burning, blurring, fatigue, ocular allergic reactions, and ocular pruritus.

The common side effects of Topical Brimonidine include erythema, flushing, skin burning sensation, and contact dermatitis.

Who should not take Brimonidine?

– People who are allergic to Brimonidine or any component of the formulation
– Neonates and infants under the age of 2 years (for eye drops)

Pharmacist Tips:

Eye drops:
– Wash your hands with soap and water before and after using.
– Shake the eye drops well just before each use.
– Remove contact lenses prior to administration, and wait 15 minutes before reinserting.
– Separate administration of other ophthalmic agents by at least 10 minutes.
– Avoid activities requiring mental alertness or coordination until drug effects are realized, such as driving.

Topical gel:
– Wash your hands with soap and water before and after using
– Do not use this medicine in your eyes, mouth, or vagina, or on skin areas that have cuts, scrapes, or burns.

Common dosing schedule:
Eye drops should be administered approximately 8 hours apart.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Brimonidine may interact with:
– Digoxin
– Beta-blockers, e.g. Metoprolol, Propranolol
– Monoamine oxidase inhibitors, e.g. Selegiline, Rasagiline
– Antihypertensives, e.g. Hydrochlorothiazide, Lisinopril

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Brimonidine in Hong Kong?

In Hong Kong, Brimonidine is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Brimonidine in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.