Medicines & Supplements A to Z > Bicalutamide

Bicalutamide

Last updated on 13/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions   |   Tips   |   Where To Buy  

GENERIC NAME: Bicalutamide

CHINESE NAME: 比卡鲁胺

BRAND NAME(S) IN HONG KONG: Casodex 康士得

DRUG CLASS: Antiandrogens, Antineoplastics

SUB CLASS: Hormone antagonists

USED FOR: Treatment of prostate cancer

AVAILABLE DOSAGE FORMS:
– 50mg, 150mg (tablets)

What is Bicalutamide for?

Bicalutamide belongs to a class of medications called hormone antagonists. It works by inhibiting a hormone in the body to stop the growth and spread of prostate cancer cells. It is indicated for the treatment of metastatic (stage D2) prostate cancer, in combination with a GnRH analogue.

How to use it?

Bicalutamide is taken orally as tablets. The usual dose is 50 mg once daily in combination with a GnRH analogue, such as Goserelin.

The use of Bicalutamide 150 mg is not common, but the use may be instructed by your doctors based on the severity.

What are the side effects of Bicalutamide?

Common side effects of Bicalutamide include hot flashes, pain, fatigue, constipation, infection, nausea, and diarrhea.

Who should not take Bicalutamide?

– People who are allergic to Bicalutamide or any component of the formulation
– Female patients

Pharmacist Tips:

– Use effective birth control to protect your female partner from pregnancy while you take this drug and for 130 days after your last dose.
– Do not drive or operate machinery until you know the effect of the medicine.
– If you have diabetes, inform your doctor before initiating treatment.
– You may get sunburned more easily. Use sunscreen and wear clothing that protects you from the sun.
– This drug may cause serious liver problems. Report any symptoms immediately such as fatigue, abdominal pain, loss of appetite, itching, bruising, and yellow skin or eyes. 

Common dosing schedule:
Bicalutamide should be taken at the same time each day, either in the morning or in the evening, with or without food. 

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Bicalutamide may interact with:
– Warfarin
– Lipid-regulating drugs, e.g. Simvastatin, Lovastatin, Atorvastain
– Benzodiazepines, e.g. Alprazolam, Midazolam
– Antifungals, e.g. Itraconazole, Ketoconazole
– Macrolide antibiotics, e.g. Clarithromycin, Erythromycin

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Bicalutamide in Hong Kong?

In Hong Kong, Bicalutamide is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Bicalutamide in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.