Medicines & Supplements A to Z > Aminophylline

Aminophylline

Last updated on 14/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Aminophylline

CHINESE NAME: 氨基非林

BRAND NAME(S) IN HONG KONG: Ampine

DRUG CLASS: Bronchodilators

SUB CLASS: Phosphodiesterase Inhibitors

USED FOR: Asthma, Chronic obstructive pulmonary disease, Bronchospasm

AVAILABLE DOSAGE FORMS:
– 250 mg/10mL (injections)

What is Aminophylline for?

Aminophylline belongs to a class of medications called phosphodiesterase inhibitors. It can relax the smooth muscle of the airways and stop the airways from reacting to external stimuli. Aminophylline is used to treat asthma, chronic obstructive pulmonary disease and bronchospasm.

How to use it?

In Hong Kong, Aminophylline is administered by healthcare professionals by injecting it through the veins. The dose is calculated based on your ideal body weight, which derives solely from your height. The dose will be further modified for the maintenance stage according to your serum level according to the physician’s judgement.

Reversible airflow obstruction
Adult and elderly
Loading dose:
Those who have not received aminophylline or theophylline in the last 24 hours: 5.7 mg/kg infused over 30 minutes.
Those who have received aminophylline or theophylline in the last 24 hours: Dose calculated based on your serum concentration infused over 30 minutes.

Maintenance dose:
0.25-0.51 mg/kg/hour.

Child
Loading dose:
Those who have not received aminophylline or theophylline in the last 24 hours: 5.7 mg/kg infused over 30 minutes.
Those who have received aminophylline or theophylline in the last 24 hours: Dose calculated based on your serum concentration infused over 30 minutes.

Maintenance dose:
0.25-1.01 mg/kg/hour.

What are the side effects of Aminophylline?

Common side effects of Aminophylline include restlessness, headache, allergic skin reaction, diarrhea, nausea, vomiting, temporary excessive sweating and tremor.

Who should not take Aminophylline?

– People allergic to Aminophylline, Theophylline, Ethylenediamine or any component of the formulation.
– Patients with peptic ulcer disease.
– Patients with coronary artery disease in which cardiac stimulation might be harmful.

Pharmacist Tips:

– Stop smoking while you are on this medication.
– For asthma patients, know what triggers your asthma and avoid them.
– Regular exercise at a moderate intensity.

Common dosing schedule:
Aminophylline injections are prescribed in institutions by the physicians.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Aminophylline may interact with:
Allopurinol
– Barbiturates, e.g. Pentobarbital, Phenobarbital, Thiopental
– Benzodiazepines, e.g. Alprazolam, Triazolam, Lorazepam
– Beta-blockers, e.g. Propranolol, Labetalol, Metoprolol
– CYP1A2 inhibitors, e.g. Ciprofloxacin, Fluvoxamine, Diltiazem

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Aminophylline in Hong Kong?

In Hong Kong, Aminophylline is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Aminophylline in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.