Medicines & Supplements A to Z > Acyclovir
Last updated on 18/03/2021.
GENERIC NAME: Acyclovir / Aciclovir
CHINESE NAME: 阿昔洛韋
BRAND NAME(S) IN HONG KONG: Entir, Zovirax
DRUG CLASS: Antiviral agent
USED FOR: Herpes simplex virus infections, varicella-zoster virus infection other DRUGS IN THE SAME CLASS: Famciclovir, Valacyclovir
AVAILABLE DOSAGE FORMS:
– 5% (cream)
– 250mg/10ml, 500mg/20ml (IV infusion)
– 200mg, 400mg, 800mg (tablets)
What is Acyclovir for?
Acyclovir is an antiviral against herpes simplex virus types 1 and 2 as well as varicella-zoster virus (herpes zoster and chickenpox). It is indicated for the following conditions:
– Treatment and prevention of herpes labialis (cold sores)
– Genital herpes
– Herpes zoster (shingles)
– Prevention of herpes simplex in immunocompromised patients (eg elderly, patients — suffering from infections, patients taking immunosuppressants)
-Herpes simplex encephalitis (inflammation of the brain)
-Herpes simplex keratitis (inflammation of the cornea)
How to use it?
Acyclovir is usually taken by mouth as a tablet. It is also available as a skin cream, which is applied to the skin, eye ointment, and an injectable formulation.
For herpes simplex keratitis
|Adult||To the eye as 3% ointment|
Apply inside the lower conjunctival sac 5 times daily every 4 hours. Continue treatment for at least 3 days upon the completion of healing.
For suppression of recurrent herpes simplex
|Adult||Oral – 800 mg daily in 2-4 divided doses and may reduce to 400-600 mg daily. Conditions should be reassessed every 6-12 months|
For mild or infrequent recurrences: 200 mg 5 times daily for 5 days, preferably begin during the prodromal period
For primary herpes simplex infections
|Adult / Child above 2 years||Oral – 200 mg 5 times daily, usually every 4 hours while awake for 5-10 days. |
For severely immunocompromised patients: 400 mg 5 times daily for 5 days
For herpes zoster (shingles)
|Adult||Oral – 800 mg 5 times daily for 7-10 days|
For varicella-zoster virus infection
|Adult||Oral – 800 mg 4 or 5 times daily for 5-7 days|
|Child above 2 years||20 mg/kg (up to a maximum of 800 mg), 4 times daily for 5 days|
For herpes simplex infections of skin
|Adult||Topical as 5% ointment / cream|
Apply 5 or 6 times daily for 5-10 days, preferably begin in the prodromal period.
What are the side effects of Acyclovir?
Common side effects of Acyclovir associated with use in the eye include eye inflammation and eye pain. Side effects of Acyclovir when taken by mouth include abdominal pain, diarrhoea, dizziness, headache, nausea, sensitivity to sunlight (photosensitivity), skin reactions, and vomiting.
Who should not take Acyclovir?
Anyone who has an allergy to acyclovir or any other components of the product.
Avoid applying other cream on top of Acyclovir cream / ointment.
Wash your hands after applying Acyclovir cream / ointment.
Common dosing schedule:
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Acyclovir may interact with:
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
Where to buy Acyclovir in Hong Kong?
In Hong Kong, Acyclovir is a prescription-only medicine and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk/
Need more information?
For detailed information about the use of Acyclovir in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.